Inflammatory mediators in various molecular pathways involved in the development of pulmonary fibrosis

MF Muneesa, SB Shaikh, TM Jeena… - International …, 2021 - Elsevier
pulmonary fibrosis: Pro-Inflammatory cytokines are responsible for activation of alveolar
inflammatory pathways. IL-17AR operates IL-17A activating the prime modulator … -γ (IFN-γ) and IL…

Prognostic significance of serum cytokines during acute exacerbation of idiopathic interstitial pneumonias treated with thrombomodulin

T Arai, H Matsuoka, M Hirose, H Kida… - BMJ Open …, 2021 - bmjopenrespres.bmj.com
… IL-10, G-CSF, IFN-γ and MCP-1 levels on day 8 was significantly … of patients with AE-IIPs who
are treated with corticosteroids … . Thrombomodulin: a bifunctional modulator of inflammation …

[HTML][HTML] Regulatory immune cells in idiopathic pulmonary fibrosis: friends or foes?

C van Geffen, A Deißler, M Quante, H Renz… - Frontiers in …, 2021 - frontiersin.org
Cytokines and growth factors activating fibroblasts and … and IL-12 (93), and IFN-γ production
by T cells was found to be … of the modulation of immune responses through modulating

Matrix metalloproteinase: An upcoming therapeutic approach for idiopathic pulmonary fibrosis

S Mahalanobish, S Saha, S Dutta, PC Sil - Pharmacological Research, 2020 - Elsevier
… regulate MMP production by modulating various cell signaling … expression (suppressor
of cytokine signaling 1) which acts … -10 although the levels of IFN-γ inducible protein-10 (CXCL10 …

Type-1 IFN primed monocytes in pathogenesis of idiopathic pulmonary fibrosis

E Fraser, L Denney, K Blirando, C Vuppusetty… - bioRxiv, 2020 - biorxiv.org
… from patients not on immunosuppressants or corticosteroids, that … We found a significant
increase in the levels of CSF-1, IL-6, and … Inhibiting or modulating CD64 expression could be a …

[HTML][HTML] The interaction between pulmonary fibrosis and COVID-19 and the application of related anti-fibrotic drugs

H Shen, N Zhang, Y Liu, X Yang, Y He, Q Li… - Frontiers in …, 2022 - frontiersin.org
… hand, the level of cytokines including Krebs von den Lungen-… exert anti-inflammatory and
immunosuppressive effects of the lung… of pulmonary fibrosis), systemic corticosteroid therapy is …

Regulatory Immune Cells in Idiopathic Pulmonary Fibrosis: Friends or Foes?

E Conte, E Tsitoura, A Byrne - … of Lung Fibrosis: is Immunity Back …, 2022 - books.google.com
Cytokines and growth factors activating fibroblasts and … and IL-12 (93), and IFN-γ
production by T cells was found to be … Modulation of cytokine and nitric oxide by mesenchymal …

[HTML][HTML] Immune dysregulation as a driver of idiopathic pulmonary fibrosis

K Shenderov, SL Collins, JD Powell… - The Journal of clinical …, 2021 - Am Soc Clin Investig
… response to infection, but corticosteroids have not been shown to … In the setting of
proinflammatory cytokines such as IFN-γ or … (Th1) responses, and modulating white and brown …

Lung transplant recipients with idiopathic pulmonary fibrosis have impaired alloreactive immune responses

P Wang, J Leung, A Lam, S Lee, DR Calabrese… - The Journal of Heart and …, 2022 - Elsevier
… from the use of immunosuppression as a treatment for IPF. Post-… cytokine production with
IPF subjects in group 3 displaying a preserved proliferative type 1 cytokine response (IL-2, IFN-γ

Novel Th17 lymphocyte populations, Th17. 1 and PD1+ Th17, are increased in Takayasu arteritis, and both Th17 and Th17. 1 sub-populations associate with active …

K Singh, U Rathore, MK Rai, MR Behera… - Journal of …, 2022 - Taylor & Francis
… followed by analysis of the cytokines IFN-γ, IL-4, IL-6, IL-17A, IL-23… and its modulation by the
addition of immunosuppressive … with corticosteroids and tacrolimus supports our hypothesis …